Curative Effects of Triphala Extract against Swim Stress-Induced Gastric Ulcers via Reduced Ulcer Index, Strengthened Gastric Mucosa and Improved Redox State in Rats

Recently, the percentage of Peptic ulcer disease not linked to either Helicobacter pylori or non-steroidal anti-inflammatory drugs has increased and signifies prominent role psychophysiological stress in establishment advancements gastric ulcers other peptic diseases. The current study was intended only develop post-treatment swim stress-induced rat model but also analyze curative effects hydro-alcoholic extract Triphala model. A developed followed by therapeutic intervention Triphala. gross evaluation tissues showed that induces significant rats could clearly be observed after 21 d self-healing. Further, findings our interventional investigations revealed exerts gastro-protective activity via decreasing index increasing protective mucus content, whereas, level/activities catalase, superoxide dismutase, glutathione malondialdehyde were ameliorated administration experimental In addition, from biochemical are well corroborated histopathological observations. conclusion, demonstrates swim-stress results development damages mucosa along with altered redox homeostasis posttreatment swim-stress-induced may later investigated promoted for human clinical applications.